In March 1999, Chinese scientist Zhu Shenggeng conducted an interesting research: simulating the evolution of the biological world at the cellular level.He used a mimetic hirudin, a small protein structure with a molecular weight of 65 amino acids that has many variants in nature.Hirudin originally had an antithrombotic function, but Zhu Shenggeng designed a laboratory condition to allow hirudin to mutate freely, automatically retain those with good antithrombotic properties, and automatically eliminate those with low antithrombotic properties.He wanted to use this to verify whether hirudin drugs can eventually produce variants with strong antithrombotic properties in the directed evolution.